Effect of Timolol on Optineurin Aggregation in Transformed Induced Pluripotent Stem Cells Derived From Patient With Familial Glaucoma | Zendy

Satoshi Inagaki | Zendy; Kazuhide Kawase | Zendy; Michinori Funato | Zendy; Junko Seki | Zendy; Chizuru Kawase | Zendy; Kazuki Ohuchi | Zendy; Tsubasa Kameyama | Zendy; Shiori Ando | Zendy; Arisu Sato | Zendy; Wataru Morozumi | Zendy; Shinsuke Nakamura | Zendy; Masamitsu Shimazawa | Zendy; Daisuke Iejima | Zendy; Takeshi Iwata | Zendy; Tetsuya Yamamoto | Zendy; Hideo Kaneko | Zendy; Hideaki Hara | Zendy

Open Access

Effect of Timolol on Optineurin Aggregation in Transformed Induced Pluripotent Stem Cells Derived From Patient With Familial Glaucoma

Author(s) -

Satoshi Inagaki,

Kazuhide Kawase,

Michinori Funato,

Junko Seki,

Chizuru Kawase,

Kazuki Ohuchi,

Tsubasa Kameyama,

Shiori Ando,

Arisu Sato,

Wataru Morozumi,

Shinsuke Nakamura,

Masamitsu Shimazawa,

Daisuke Iejima,

Takeshi Iwata,

Tetsuya Yamamoto,

Hideo Kaneko,

Hideaki Hara

Publication year - 2018

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.17-22975

Subject(s) - optineurin , timolol , induced pluripotent stem cell , microbiology and biotechnology , blot , autophagy , chemistry , glaucoma , apoptosis , biology , biochemistry , neuroscience , embryonic stem cell , gene

To determine a chemical agent that can reduce the aggregation of optineurin (OPTN) in cells differentiated from induced pluripotent stem cells obtained from a patient with normal-tension glaucoma (NTG) caused by an E50K mutation in the OPTN gene (OPTNE50K-NTG).

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research