The Influence of Age and Sex on Ocular Surface Microbiota in Healthy Adults
Author(s) -
Xiaofeng Wen,
Miao Li,
Yuhua Deng,
Paul W. Bible,
Xiao Hu,
Yanli Zou,
Yu Liu,
Shixin Guo,
Juanran Liang,
Tingting Chen,
Guang-Hua Peng,
Wei Chen,
Lingyi Liang,
Lai Wei
Publication year - 2017
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.17-22957
Subject(s) - microbiome , conjunctiva , biology , metagenomics , young adult , physiology , pathogenesis , shotgun sequencing , immunology , medicine , gene , bioinformatics , genetics , dna sequencing
A growing body of evidence suggests that the microbiome of the ocular surface confers potent immunoregulatory functions and has a key role in the physiologic maintenance of healthy eyes and in the pathogenesis of ocular diseases. Although the microbiome is known to be affected by age and sex, the influence of these factors on ocular surface microbiota in healthy adults remains largely unknown.
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