Sustained Connexin43 Mimetic Peptide Release From Loaded Nanoparticles Reduces Retinal and Choroidal Photodamage | Zendy

Nasir Mat Nor | Zendy; Cindy X. Guo | Zendy; Ilva D. Rupenthal | Zendy; Ying-Shan Chen | Zendy; Colin Green | Zendy; Mónica L. Acosta | Zendy

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Sustained Connexin43 Mimetic Peptide Release From Loaded Nanoparticles Reduces Retinal and Choroidal Photodamage

Author(s) -

Nasir Mat Nor,

Cindy X. Guo,

Ilva D. Rupenthal,

Ying-Shan Chen,

Colin Green,

Mónica L. Acosta

Publication year - 2018

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.17-22829

Subject(s) - retina , retinal , glial fibrillary acidic protein , inflammation , erg , electroretinography , ophthalmology , outer nuclear layer , chemistry , in vivo , medicine , pathology , immunohistochemistry , immunology , biology , neuroscience , microbiology and biotechnology

To evaluate the long-term effect on inflammation and inflammasome activation of intravitreally delivered connexin43 mimetic peptide (Cx43MP) in saline or incorporated within nanoparticles (NPs) for the treatment of the light-damaged rat eye.

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