Leucine-Rich α-2-Glycoprotein-1 (LRG-1) Expression in Retinoblastoma | Zendy

Radgonde Amer | Zendy; Liran Tiosano | Zendy; Jacob Pe’er | Zendy

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Leucine-Rich α-2-Glycoprotein-1 (LRG-1) Expression in Retinoblastoma

Author(s) -

Radgonde Amer,

Liran Tiosano,

Jacob Pe’er

Publication year - 2018

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.17-22785

Subject(s) - retinoblastoma , leucine , glycoprotein , expression (computer science) , chemistry , microbiology and biotechnology , biology , biochemistry , computer science , gene , amino acid , programming language

Retinoblastomas' growth rate is dependent on their ability to induce neovascularization. Leucine-rich α-2-glycoprotein-1 (LRG-1) was recently reported to be upregulated in human retinal disease with neovascular pathology. The purpose of the study was to determine LRG-1 expression in human retinoblastoma and to correlate it with clinical and histopathologic parameters and to assess how its expression correlates with vascular endothelial growth factor (VEGF) expression.

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