Human Conjunctival Epithelial Sheets Grown on Poly(Lactic-Co-Glycolic) Acid Membranes and Cocultured With Human Tenon's Fibroblasts for Corneal Repair | Zendy

Soyoung Hong | Zendy; Je Hwan Yun | Zendy; EunSoon Kim | Zendy; Ji Seon Kim | Zendy; Hungwon Tchah | Zendy; Changmo Hwang | Zendy

Open Access

Human Conjunctival Epithelial Sheets Grown on Poly(Lactic-Co-Glycolic) Acid Membranes and Cocultured With Human Tenon's Fibroblasts for Corneal Repair

Author(s) -

Soyoung Hong,

Je Hwan Yun,

EunSoon Kim,

Ji Seon Kim,

Hungwon Tchah,

Changmo Hwang

Publication year - 2018

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.17-22719

Subject(s) - plga , epithelium , corneal epithelium , transplantation , wound healing , in vivo , ex vivo , cell , cornea , chemistry , in vitro , pathology , microbiology and biotechnology , biology , medicine , ophthalmology , immunology , surgery , biochemistry

We determine the feasibility of human conjunctival epithelial cells (hCjECs) on poly(lactic-co-glycolic) acid (PLGA) membranes for corneal epithelium regeneration. hCjECs on PLGA or polyester (PET) membranes with or without coculture of human Tenon's fibroblasts (hTFs) were compared in vitro, and to determine whether epithelial sheets grown on PLGA membranes can repair injured rabbit corneal epithelium by transplantation for 2 weeks in vivo.

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