Expression and Regulation of S100 Fused-Type Protein Hornerin at the Ocular Surface and Lacrimal Apparatus | Zendy

Fabian Garreis | Zendy; J. Jahn | Zendy; Katharina Wild | Zendy; D Abrar | Zendy; Martin Schicht | Zendy; JensMichael Schröder | Zendy; Friedrich Paulsen | Zendy

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Expression and Regulation of S100 Fused-Type Protein Hornerin at the Ocular Surface and Lacrimal Apparatus

Author(s) -

Fabian Garreis,

J. Jahn,

Katharina Wild,

D Abrar,

Martin Schicht,

JensMichael Schröder,

Friedrich Paulsen

Publication year - 2017

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.17-22637

Subject(s) - meibomian gland , cornea , lacrimal apparatus , conjunctiva , biology , corneal epithelium , epithelium , lacrimal gland , immunohistochemistry , pathology , microbiology and biotechnology , eyelid , immunology , medicine , ophthalmology , neuroscience

The S100 fused-type proteins hornerin (HRNR) and filaggrin-2 (FLG2) are members of the epidermal differentiation complex, which is involved in terminal differentiation of keratinocytes via cornification as well as maintenance of the epidermal antimicrobial barrier. We investigated the expression and possible regulation of HRNR and FLG2 at the ocular surface and in the lacrimal apparatus.

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