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Platelet-Derived Growth Factor-BB Lessens Light-Induced Rod Photoreceptor Damage in Mice
Author(s) -
Kei Takahashi,
Masamitsu Shimazawa,
Hiroshi Izawa,
Yuki Inoue,
Yoshiki Kuse,
Hideaki Hara
Publication year - 2017
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.17-22556
Subject(s) - platelet derived growth factor receptor , outer nuclear layer , photoreceptor cell , platelet derived growth factor , growth factor , electroretinography , retinal , cell damage , retina , microbiology and biotechnology , chemistry , biology , biophysics , biochemistry , neuroscience , receptor
Platelet-derived growth factor (PDGF)-BB is known to have neuroprotective effects against various neurodegenerative disorders. The purpose of this study was to determine whether PDGF-BB can be neuroprotective against light-induced photoreceptor damage in mice.

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