Mesopic and Photopic Rod and Cone Photoreceptor-Driven Visual Processes in Mice With Long-Wavelength–Shifted Cone Pigments | Zendy

Tina I. Tsai | Zendy; Anneka Joachimsthaler | Zendy; Jan Kremers | Zendy

Open Access

Mesopic and Photopic Rod and Cone Photoreceptor-Driven Visual Processes in Mice With Long-Wavelength–Shifted Cone Pigments

Author(s) -

Tina I. Tsai,

Anneka Joachimsthaler,

Jan Kremers

Publication year - 2017

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.17-22553

Subject(s) - photopic vision , luminance , electroretinography , visual phototransduction , mesopic vision , stimulus (psychology) , physics , optics , amplitude , spectral sensitivity , spatial frequency , biophysics , retina , biology , wavelength , psychology , psychotherapist

The clearer divergence in spectral sensitivity between native rod and human L-cone (L*-cone) opsins in the transgenic Opn1lwLIAIS mouse (LIAIS) allows normal visual processes mediated by these photoreceptor subtypes to be isolated effectively using the silent substitution technique. The objective of this study was to further characterize the influence of mean luminance and temporal frequency on the functional properties of signals originating in each photoreceptor separately and independently of adaptation state in LIAIS mice.

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