The Transcription Factor Prdm16 Marks a Single Retinal Ganglion Cell Subtype in the Mouse Retina | Zendy

Sergio Groman-Lupa | Zendy; Joseph Adewumi | Zendy; Ko Uoon Park | Zendy; Joseph A. Brzezinski | Zendy

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The Transcription Factor Prdm16 Marks a Single Retinal Ganglion Cell Subtype in the Mouse Retina

Author(s) -

Sergio Groman-Lupa,

Joseph Adewumi,

Ko Uoon Park,

Joseph A. Brzezinski

Publication year - 2017

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.17-22442

Subject(s) - biology , retina , ganglion cell layer , microbiology and biotechnology , ganglion , intrinsically photosensitive retinal ganglion cells , giant retinal ganglion cells , retinal ganglion cell , anatomy , neuroscience

Retinal ganglion cells (RGC) can be categorized into roughly 30 distinct subtypes. How these subtypes develop is poorly understood, in part because few unique subtype markers have been characterized. We tested whether the Prdm16 transcription factor is expressed by RGCs as a class or within particular ganglion cell subtypes.

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