Open AccessPharmacokinetic and Safety Evaluation of a Transscleral Sustained Unoprostone Release Device in Monkey Eyes
Author(s) -
Nobuhiro Nagai,
Shinji Yamada,
Junichi Kawasaki,
Eri Koyanagi,
Saaya Saijo,
Hirokazu Kaji,
Matsuhiko Nishizawa,
Toru Nakazawa,
Toshiaki Abe
Publication year - 2018
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.17-22429
Subject(s) - ophthalmology , pharmacokinetics , medicine , optometry , pharmacology
We evaluate the ocular tissue distribution and retinal toxicity of unoprostone (UNO) during 12 months, after transscleral sustained-UNO administration using a drug delivery device in monkey eyes.
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