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Evidence for Cerebrospinal Fluid Entry Into the Optic Nerve via a Glymphatic Pathway
Author(s) -
Emily Mathieu,
Neeru Gupta,
Amir Ahari,
Xun Zhou,
Joseph Hanna,
Yeni H. Yücel
Publication year - 2017
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.17-22290
Subject(s) - glymphatic system , optic nerve , cerebrospinal fluid , pathology , subarachnoid space , glial fibrillary acidic protein , fluorescein isothiocyanate , chemistry , immunostaining , aquaporin 4 , tracer , anatomy , biology , medicine , immunohistochemistry , fluorescence , physics , quantum mechanics , nuclear physics
The purpose of this study was to determine whether cerebrospinal fluid (CSF) enters the optic nerve via a glymphatic pathway and whether this entry is size-dependent.

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