Inflammatory and Neuronal Biomarkers Associated With Retinal Thinning in Pediatric HIV | Zendy

Charlotte Blokhuis | Zendy; Susanne Doeleman | Zendy; Sophie Cohen | Zendy; Nazli Demirkaya | Zendy; Henriëtte J. Scherpbier | Zendy; Neeltje A. Kootstra | Zendy; Jens Kühle | Zendy; Charlotte E. Teunissen | Zendy; Frank D. Verbraak | Zendy; Dasja Pajkrt | Zendy

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Inflammatory and Neuronal Biomarkers Associated With Retinal Thinning in Pediatric HIV

Author(s) -

Charlotte Blokhuis,

Susanne Doeleman,

Sophie Cohen,

Nazli Demirkaya,

Henriëtte J. Scherpbier,

Neeltje A. Kootstra,

Jens Kühle,

Charlotte E. Teunissen,

Frank D. Verbraak,

Dasja Pajkrt

Publication year - 2017

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.17-22252

Subject(s) - medicine , inflammation , retinal , pathophysiology , immune system , inner plexiform layer , pathology , immunology , ophthalmology

The pathophysiology of neuroretinal thinning in children with human immunodeficiency virus (HIV) is poorly understood. The current study aimed to assess whether neuroretinal thinning in clinically stable perinatally HIV-infected children was associated with biomarkers of immune activation, inflammation, and neuronal damage.

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