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Effects of Prenatal Alcohol Exposure on the Visual System of Monkeys Measured at Different Stages of Development
Author(s) -
Vanessa Harrar,
Laurent Elkrief,
Joseph Bouskila,
Ryan Kucera,
Anders FinkJensen,
JeanFrançois Bouchard,
Roberta M. Palmour,
Maurice Ptito
Publication year - 2017
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.17-22181
Subject(s) - scotopic vision , photopic vision , electroretinography , erg , retina , retinal , audiology , prenatal alcohol exposure , physiology , psychology , medicine , ophthalmology , alcohol , biology , neuroscience , biochemistry
Fetal alcohol spectrum disorder (FASD) is a developmental disease characterized by behavioral problems and physical defects including malformations of the eye and associated optical defects. How these malformations affect retinal functioning is not well known, although animal models have suggested that scotopic vision is particularly deficient. Age is also known to affect scotopic vision. Here, we determined the combined effects of age and fetal alcohol exposure (FAE) on retinal function using full-field electroretinograms (ERGs) in monkeys (Chlorocebus sabaeus).

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