Glucocorticoid-Induced Leucine Zipper Protects the Retina From Light-Induced Retinal Degeneration by Inducing Bcl-xL in Rats | Zendy

Ruiping Gu | Zendy; Wenyi Tang | Zendy; Boya Lei | Zendy; Xinyi Ding | Zendy; Cheng Jiang | Zendy; Gezhi Xu | Zendy

Open Access

Glucocorticoid-Induced Leucine Zipper Protects the Retina From Light-Induced Retinal Degeneration by Inducing Bcl-xL in Rats

Author(s) -

Ruiping Gu,

Wenyi Tang,

Boya Lei,

Xinyi Ding,

Cheng Jiang,

Gezhi Xu

Publication year - 2017

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.17-22116

Subject(s) - downregulation and upregulation , retina , retinal , retinal degeneration , small hairpin rna , erg , microbiology and biotechnology , leucine zipper , electroretinography , biology , apoptosis , outer nuclear layer , chemistry , neuroscience , biochemistry , transcription factor , gene knockdown , gene

The aim of the present study was to investigate the neuroprotective effects of glucocorticoid-induced leucine zipper (GILZ) in a light-induced retinal degeneration model and to explore the underlying mechanisms.

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