Proteasome Inhibition Increases the Efficiency of Lentiviral Vector-Mediated Transduction of Trabecular Meshwork | Zendy

Zeynep Aktaş | Zendy; Hongyu Rao | Zendy; Sarah Slauson | Zendy; B’Ann T. Gabelt | Zendy; Inna V. Larsen | Zendy; Rachael Sheridan | Zendy; Leonie Herrnberger | Zendy; Ernst R. Tamm | Zendy; Paul L. Kaufman | Zendy; Curtis R. Brandt | Zendy

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Proteasome Inhibition Increases the Efficiency of Lentiviral Vector-Mediated Transduction of Trabecular Meshwork

Author(s) -

Zeynep Aktaş,

Hongyu Rao,

Sarah Slauson,

B’Ann T. Gabelt,

Inna V. Larsen,

Rachael Sheridan,

Leonie Herrnberger,

Ernst R. Tamm,

Paul L. Kaufman,

Curtis R. Brandt

Publication year - 2018

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.17-22074

Subject(s) - transduction (biophysics) , mg132 , green fluorescent protein , microbiology and biotechnology , proteasome inhibitor , trabecular meshwork , biology , viral vector , proteasome , gene delivery , cell culture , chemistry , transfection , gene , biochemistry , genetics , recombinant dna , neuroscience , glaucoma

To determine if proteasome inhibition using MG132 increased the efficiency of FIV vector-mediated transduction in human trabecular meshwork (TM)-1 cells and monkey organ-cultured anterior segments (MOCAS).

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