Conditionally Immortal Slc4a11−/− Mouse Corneal Endothelial Cell Line Recapitulates Disrupted Glutaminolysis Seen in Slc4a11−/− Mouse Model | Zendy

Wenlin Zhang | Zendy; Diego G. Ogando | Zendy; Edward T. Kim | Zendy; Moonjung Choi | Zendy; Hongde Li | Zendy; Jason M. Tenessen | Zendy; Joseph A. Bonanno | Zendy

Open Access

Conditionally Immortal Slc4a11^−/− Mouse Corneal Endothelial Cell Line Recapitulates Disrupted Glutaminolysis Seen in Slc4a11^−/− Mouse Model

Author(s) -

Wenlin Zhang,

Diego G. Ogando,

Edward T. Kim,

Moonjung Choi,

Hongde Li,

Jason M. Tenessen,

Joseph A. Bonanno

Publication year - 2017

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.17-21781

Subject(s) - glutaminolysis , corneal endothelium , chemistry , cell culture , microbiology and biotechnology , biology , glutamine , endothelium , biochemistry , endocrinology , genetics , amino acid

To establish conditionally immortal mouse corneal endothelial cell lines with genetically matched Slc4a11+/+ and Slc4a11-/- mice as a model for investigating pathology and therapies for SLC4A11 associated congenital hereditary endothelial dystrophy (CHED) and Fuchs' endothelial corneal dystrophy.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research