Molecular Pathway to Protection From Age-Dependent Photoreceptor Degeneration in Mef2 Deficiency | Zendy

Saumya Nagar | Zendy; Dorit Trudler | Zendy; Scott R. McKercher | Zendy; Juan C. PiñaCrespo | Zendy; Nobuki Nakanishi | Zendy; Shuichi Okamoto | Zendy; Stuart A. Lipton | Zendy

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Molecular Pathway to Protection From Age-Dependent Photoreceptor Degeneration in Mef2 Deficiency

Author(s) -

Saumya Nagar,

Dorit Trudler,

Scott R. McKercher,

Juan C. PiñaCrespo,

Nobuki Nakanishi,

Shuichi Okamoto,

Stuart A. Lipton

Publication year - 2017

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.17-21767

Subject(s) - biology , mef2 , microbiology and biotechnology , chromatin immunoprecipitation , neuroprotection , retinal degeneration , retina , outer nuclear layer , retinal , transcription factor , genetics , neuroscience , gene expression , gene , biochemistry , promoter , enhancer

Photoreceptor degeneration in the retina is a major cause of blindness in humans. Elucidating mechanisms of degenerative and neuroprotective pathways in photoreceptors should afford identification and development of therapeutic strategies.

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