Genetic African Ancestry Is Associated With Central Corneal Thickness and Intraocular Pressure in Primary Open-Angle Glaucoma
Author(s) -
Pieter W. M. Bonnemaijer,
Colin Cook,
Abhishek Nag,
Christopher J. Hammond,
Cornelia M. van Duijn,
Hans G. Lemij,
Caroline C. W. Klaver,
Alberta A. H. J. Thiadens
Publication year - 2017
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.17-21716
Subject(s) - intraocular pressure , ophthalmology , glaucoma , logistic regression , open angle glaucoma , medicine , population , single nucleotide polymorphism , ocular hypertension , biology , genotype , genetics , gene , environmental health
To unravel the relationship between African ancestry, central corneal thickness (CCT), and intraocular pressure (IOP) by estimating the genetic African ancestry (GAA) proportion in primary open-angle glaucoma (POAG) patients and controls from an admixed South African Colored (SAC) and a South African Black (SAB) population.
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