Urinary Isoprostane Levels and Age-Related Macular Degeneration | Zendy

Charumathi Sabanayagam | Zendy; Weng Kit Lye | Zendy; Andrzej S. Januszewski | Zendy; Riswana Banu Binte Mohammed Abdul | Zendy; Chui Ming Gemmy Cheung | Zendy; Kumari Neelam | Zendy; Tien Yin Wong | Zendy; ChingYu Cheng | Zendy; Ecosse L. Lamoureux | Zendy

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Urinary Isoprostane Levels and Age-Related Macular Degeneration

Author(s) -

Charumathi Sabanayagam,

Weng Kit Lye,

Andrzej S. Januszewski,

Riswana Banu Binte Mohammed Abdul,

Chui Ming Gemmy Cheung,

Kumari Neelam,

Tien Yin Wong,

ChingYu Cheng,

Ecosse L. Lamoureux

Publication year - 2017

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.16-21263

Subject(s) - odds ratio , medicine , body mass index , macular degeneration , confidence interval , confounding , quartile , urinary system , creatinine , gastroenterology , endocrinology , physiology , ophthalmology

Oxidative stress, characterized by an excessive production of reactive oxygen intermediates has been suggested to play a role in the pathogenesis of age-related macular degeneration (AMD). We examined the association of urinary F2-isoprostanes (F2-IsoPs), a marker of lipid peroxidation and the most reliable marker of oxidative damage with AMD.

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