Compromised Integrity of Central Visual Pathways in Patients With Macular Degeneration | Zendy

Maka Malania | Zendy; Julia Konrad | Zendy; Herbert Jägle | Zendy; John S. Werner | Zendy; Mark W. Greenlee | Zendy

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Compromised Integrity of Central Visual Pathways in Patients With Macular Degeneration

Author(s) -

Maka Malania,

Julia Konrad,

Herbert Jägle,

John S. Werner,

Mark W. Greenlee

Publication year - 2017

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.16-21191

Subject(s) - diffusion mri , nerve fiber layer , visual system , retinal , ophthalmology , retina , optic tract , white matter , neuroscience , fractional anisotropy , retinal degeneration , optic nerve , macular degeneration , optic radiation , corpus callosum , medicine , anatomy , lateral geniculate nucleus , optical coherence tomography , magnetic resonance imaging , psychology , radiology

Macular degeneration (MD) affects the central retina and leads to gradual loss of foveal vision. Although, photoreceptors are primarily affected in MD, the retinal nerve fiber layer (RNFL) and central visual pathways may also be altered subsequent to photoreceptor degeneration. Here we investigate whether retinal damage caused by MD alters microstructural properties of visual pathways using diffusion-weighted magnetic resonance imaging.

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