Asymmetric Inter-Eye Progression in Stargardt Disease
Author(s) -
Stanley Lambertus,
Nathalie M. Bax,
J.M.M. Groenewoud,
Frans P.M. Cremers,
Gert Jan van der Wilt,
B. Jeroen Klevering,
Thomas Theelen,
Carel B. Hoyng
Publication year - 2016
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.16-20963
Subject(s) - stargardt disease , abca4 , atrophy , medicine , ophthalmology , pathology , macular degeneration , biology , genetics , gene , phenotype
Asymmetry in disease progression between left and right eyes can occur in Stargardt disease (STGD1), and this needs to be considered in novel therapeutic trials with a fellow-eye paired controlled design. This study investigated the inter-eye discordance of best-corrected visual acuity (BCVA) and progression of RPE atrophy in STGD1.
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