Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells | Zendy

Ruiping Gu | Zendy; Boya Lei | Zendy; Chen Jiang | Zendy; Gezhi Xu | Zendy

Open Access

Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells

Author(s) -

Ruiping Gu,

Boya Lei,

Chen Jiang,

Gezhi Xu

Publication year - 2017

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.16-20933

Subject(s) - small hairpin rna , leucine zipper , dephosphorylation , microbiology and biotechnology , gene silencing , nfkb1 , chemistry , biology , phosphorylation , cell culture , phosphatase , transcription factor , gene knockdown , biochemistry , genetics , gene

Glucocorticoid-induced leucine zipper (GILZ) is involved in anti-inflammatory activities in several animal models and in various cell types. In this study, we explored the role of GILZ in rat retinal vascular endothelial cells.

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