Noninvasive Quantification of Retinal Microglia Using Widefield Autofluorescence Imaging | Zendy

Despina Kokona | Zendy; Nadia Schneider | Zendy; Helena Giannakaki-Zimmermann | Zendy; Joël Jovanovic | Zendy; Andreas Ebneter | Zendy; Martin S. Zinkernagel | Zendy

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Noninvasive Quantification of Retinal Microglia Using Widefield Autofluorescence Imaging

Author(s) -

Despina Kokona,

Nadia Schneider,

Helena Giannakaki-Zimmermann,

Joël Jovanovic,

Andreas Ebneter,

Martin S. Zinkernagel

Publication year - 2017

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.16-20916

Subject(s) - microglia , ex vivo , autofluorescence , retinal , in vivo , green fluorescent protein , retina , pathology , preclinical imaging , transplantation , confocal , confocal microscopy , medicine , biology , microbiology and biotechnology , ophthalmology , fluorescence , immunology , neuroscience , optics , surgery , inflammation , biochemistry , physics , gene

To validate widefield autofluorescence (AF) in vivo imaging of the retina in mice expressing green fluorescent protein (gfp) in microglia, and to monitor retinal microglia reconstitution in vivo after lethal irradiation and bone marrow transplantation.

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