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VEGF as a Paracrine Regulator of Conventional Outflow Facility
Author(s) -
Ester ReinaTorres,
Joanne C. Wen,
Katy C. Liu,
Guorong Li,
Joseph M. Sherwood,
Jason Y.H. Chang,
Pratap Challa,
Cassandra FlügelKoch,
W. Daniel Stamer,
R. Rand Allingham,
Darryl R. Overby
Publication year - 2017
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.16-20779
Subject(s) - paracrine signalling , trabecular meshwork , vascular endothelial growth factor , autocrine signalling , secretion , vascular permeability , regulator , chemistry , endocrinology , microbiology and biotechnology , vascular endothelial growth factor a , medicine , vegf receptors , receptor , biology , ophthalmology , glaucoma , biochemistry , gene
Vascular endothelial growth factor (VEGF) regulates microvascular endothelial permeability, and the permeability of Schlemm's canal (SC) endothelium influences conventional aqueous humor outflow. We hypothesize that VEGF signaling regulates outflow facility.

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