Subcellular Localization of a 2-Arachidonoyl Glycerol Signaling Cassette in Retinal Ganglion Cell Axonal Growth In Vitro
Author(s) -
David T. Stark,
Joseph Caprioli
Publication year - 2016
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.16-20748
Subject(s) - monoacylglycerol lipase , axon , endocannabinoid system , retinal ganglion cell , growth cone , diacylglycerol lipase , microbiology and biotechnology , biology , retina , diacylglycerol kinase , immunocytochemistry , receptor , medicine , neuroscience , signal transduction , endocrinology , biochemistry , protein kinase c
To investigate whether the subcellular distribution of endocannabinoid (eCB) system (ECS) components in growing RGC axons is consistent with the formation of eCB-enriched "hotspots" and the role of the ECS in RGC axonal growth.
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