MicroRNA Expression Profile in Conjunctival Melanoma | Zendy

AnnCathrine Larsen | Zendy; Lauge Hjorth Mikkelsen | Zendy; Rehannah Borup | Zendy; Katalin Kiss | Zendy; Peter Bjerre Toft | Zendy; Christian von Buchwald | Zendy; Sarah E. Coupland | Zendy; Jan Ulrik Prause | Zendy; Steffen Heegaard | Zendy

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MicroRNA Expression Profile in Conjunctival Melanoma

Author(s) -

AnnCathrine Larsen,

Lauge Hjorth Mikkelsen,

Rehannah Borup,

Katalin Kiss,

Peter Bjerre Toft,

Christian von Buchwald,

Sarah E. Coupland,

Jan Ulrik Prause,

Steffen Heegaard

Publication year - 2016

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.16-19862

Subject(s) - microrna , melanoma , microarray , downregulation and upregulation , stage (stratigraphy) , biology , epigenetics , metastasis , microarray analysis techniques , cancer research , pathogenesis , pathology , gene expression , medicine , cancer , gene , genetics , paleontology

Conjunctival melanoma (CM) is a rare disease associated with considerable mortality. As opposed to cutaneous melanoma, the epigenetic mechanisms involved in the development of CM and other mucosal melanomas (MMs) are unclear. The purpose of this study was to identify tumor-specific and prognostic microRNA (miRNA) in CM and to compare the miRNA profile with that of MM.

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