The Role of Retinal Dopamine in C57BL/6 Mouse Refractive Development as Revealed by Intravitreal Administration of 6-Hydroxydopamine | Zendy

Xiaohua Wu | Zendy; Kang-Wei Qian | Zendy; Guozhong Xu | Zendy; Yunyun Li | Zendy; Yuanyuan Ma | Zendy; Furong Huang | Zendy; Yan-Qing Wang | Zendy; Xiangtian Zhou | Zendy; Jia Qu | Zendy; Xiong-Li Yang | Zendy; YongMei Zhong | Zendy; Shi-Jun Weng | Zendy

Open Access

The Role of Retinal Dopamine in C57BL/6 Mouse Refractive Development as Revealed by Intravitreal Administration of 6-Hydroxydopamine

Author(s) -

Xiaohua Wu,

Kang-Wei Qian,

Guozhong Xu,

Yunyun Li,

Yuanyuan Ma,

Furong Huang,

Yan-Qing Wang,

Xiangtian Zhou,

Jia Qu,

Xiong-Li Yang,

YongMei Zhong,

Shi-Jun Weng

Publication year - 2016

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.16-19543

Subject(s) - retinal , ophthalmology , cornea , retina , dopamine , hydroxydopamine , retinal degeneration , vitreous chamber , erg , refractive error , electroretinography , medicine , endocrinology , chemistry , biology , dopaminergic , neuroscience , eye disease

Although retinal dopamine (DA) has been long implicated in myopia development, current studies demonstrate that retinal DA levels are unaltered in C57BL/6 mice with form-deprivation myopia. This work was undertaken to explore whether and how refractive development is perturbed in this mouse strain when retinal DA levels are reduced by 6-hydroxydopamine (6-OHDA) administration.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research