Open AccessSoluble Adenylyl Cyclase Is Required for Retinal Ganglion Cell and Photoreceptor Differentiation
Author(s) -
Peter X. Shaw,
Jiahua Fang,
Alan Sang,
Yan Wang,
Michael S. Kapiloff,
Jeffrey L. Goldberg
Publication year - 2016
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.16-19465
Subject(s) - retinal , retina , biology , retinal ganglion cell , ganglion cell layer , microbiology and biotechnology , neuroscience , biochemistry
We have previously demonstrated that soluble adenylyl cyclase (sAC) is necessary for retinal ganglion cell (RGC) survival and axon growth. Here, we further investigate the role of sAC in neuronal differentiation during retinal development.
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