A Genome-Wide Association Study Provides New Evidence That CACNA1C Gene is Associated With Diabetic Cataract | Zendy

Cheng Chang | Zendy; Kaida Zhang | Zendy; Abirami Veluchamy | Zendy; Harry L. Hébert | Zendy; Helen C. Looker | Zendy; Helen M. Colhoun | Zendy; Nicholette D. Palmer | Zendy; Weihua Meng | Zendy

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A Genome-Wide Association Study Provides New Evidence That CACNA1C Gene is Associated With Diabetic Cataract

Author(s) -

Cheng Chang,

Kaida Zhang,

Abirami Veluchamy,

Harry L. Hébert,

Helen C. Looker,

Helen M. Colhoun,

Nicholette D. Palmer,

Weihua Meng

Publication year - 2016

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.16-19332

Subject(s) - medicine , diabetes mellitus , cataracts , cohort , type 2 diabetes , cataract surgery , cataract extraction , cohort study , ophthalmology , endocrinology

Diabetic cataract is one of the major eye complications of diabetes. It was reported that cataract occurs two to five times more frequently in patients with diabetes compared with those with no diabetes. The purpose of this study was to identify genetic contributors of diabetic cataract based on a genome-wide association approach using a well-defined Scottish diabetic cohort.

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