Frizzled3Shapes the Development of Retinal Rod Bipolar Cells | Zendy

Ning Shen | Zendy; Yibo Qu | Zendy; Yankun Yu | Zendy; KwokFai So | Zendy; André M. Goffinet | Zendy; Noga Vardi | Zendy; Ying Xu | Zendy; Libing Zhou | Zendy

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Frizzled3Shapes the Development of Retinal Rod Bipolar Cells

Author(s) -

Ning Shen,

Yibo Qu,

Yankun Yu,

KwokFai So,

André M. Goffinet,

Noga Vardi,

Ying Xu,

Libing Zhou

Publication year - 2016

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.16-19281

Subject(s) - retina , immunostaining , retinal , microbiology and biotechnology , retinal ganglion cell , biology , anatomy , chemistry , neuroscience , immunohistochemistry , immunology , biochemistry

Frizzled3 (Fzd3), a member of the core planar cell polarity (PCP) family in mammals, contributes to visual development by guiding axonal projections of some retinal ganglion cells. However, its other functions in the maturation of the visual system, especially the retina, remain elusive. The present study explores the role of Fzd3 in retinal development by focusing on rod bipolar cells (RBCs).

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