Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats | Zendy

Biju B. Thomas | Zendy; Danhong Zhu | Zendy; Li Zhang | Zendy; Padmaja B. Thomas | Zendy; Yuntao Hu | Zendy; Hossein Nazari | Zendy; Francisco Rosa Stefanini | Zendy; Paulo Falabella | Zendy; Dennis Clegg | Zendy; David R. Hinton | Zendy; Mark S. Humayun | Zendy

Open Access

Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats

Author(s) -

Biju B. Thomas,

Danhong Zhu,

Li Zhang,

Padmaja B. Thomas,

Yuntao Hu,

Hossein Nazari,

Francisco Rosa Stefanini,

Paulo Falabella,

Dennis Clegg,

David R. Hinton,

Mark S. Humayun

Publication year - 2016

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.16-19238

Subject(s) - retinal , retina , retinal pigment epithelium , embryonic stem cell , biology , ophthalmology , medicine , biochemistry , gene , neuroscience

To determine the safety, survival, and functionality of human embryonic stem cell-derived RPE (hESC-RPE) cells seeded on a polymeric substrate (rCPCB-RPE1 implant) and implanted into the subretinal (SR) space of Royal College of Surgeons (RCS) rats.

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