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Increased Ocular Levels of MicroRNA-148a in Cases of Retinal Detachment Promote Epithelial–Mesenchymal Transition
Author(s) -
Kei Takayama,
Hiroki Kaneko,
Shiang-Jyi Hwang,
Fuxiang Ye,
Akiko Higuchi,
Taichi Tsunekawa,
T. Matsuura,
Takeshi Iwase,
Tetsu Asami,
Yasuki Ito,
Shinji Ueno,
Shunsuke Yasuda,
Norie obe,
Hiroko Terasaki
Publication year - 2016
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.15-18660
Subject(s) - microrna , blot , epithelial–mesenchymal transition , transfection , retinal detachment , proliferative vitreoretinopathy , microbiology and biotechnology , medicine , pathology , downregulation and upregulation , retinal , biology , cell culture , ophthalmology , gene , biochemistry , genetics
The purpose of this study was to determine microRNA expression in vitreous and subretinal fluid (SRF) samples from patients with retinal detachment (RD). The pathological importance of the identified microRNA transcript levels was analyzed in vitro.

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