Induction of Chemokine Secretion and Monocyte Migration by Human Choroidal Melanocytes in Response to Proinflammatory Cytokines
Author(s) -
Tina Jehs,
Carsten Faber,
Maja Søberg Udsen,
Martine J. Jager,
Simon J. Clark,
Morten Nissen
Publication year - 2016
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.15-18524
Subject(s) - proinflammatory cytokine , chemokine , cxcl10 , monocyte , ccl5 , ccl2 , secretion , tumor necrosis factor alpha , interleukin 8 , immunology , microbiology and biotechnology , biology , cytokine , t cell , chemistry , inflammation , immune system , endocrinology , il 2 receptor
To determine to which extent inflammatory cytokines affect chemokine secretion by primary human choroidal melanocytes (HCMs), their capacity to attract monocytes, and whether HCMs are able to influence the proliferation of activated T cells.
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