Proteomic Analysis of Lipid Raft-Like Detergent-Resistant Membranes of Lens Fiber Cells | Zendy

Zhen Wang | Zendy; Kevin L. Schey | Zendy

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Proteomic Analysis of Lipid Raft-Like Detergent-Resistant Membranes of Lens Fiber Cells

Author(s) -

Zhen Wang,

Kevin L. Schey

Publication year - 2015

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.15-18273

Subject(s) - lipid raft , raft , membrane , membrane protein , proteome , chemistry , biochemistry , microbiology and biotechnology , biology , organic chemistry , copolymer , polymer

Plasma membranes of lens fiber cells have high levels of long-chain saturated fatty acids, cholesterol, and sphingolipids-key components of lipid rafts. Thus, lipid rafts are expected to constitute a significant portion of fiber cell membranes and play important roles in lens biology. The purpose of this study was to characterize the lens lipid raft proteome.

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