3D Corneal Shape After Implantation of a Biosynthetic Corneal Stromal Substitute | Zendy

Jeb Alden Ong | Zendy; Edouard Auvinet | Zendy; Karolyn J. Forget | Zendy; Neil Lagali | Zendy; Per Fagerholm | Zendy; May Griffith | Zendy; Jean Meunier | Zendy; Isabelle Brunette | Zendy

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3D Corneal Shape After Implantation of a Biosynthetic Corneal Stromal Substitute

Author(s) -

Jeb Alden Ong,

Edouard Auvinet,

Karolyn J. Forget,

Neil Lagali,

Per Fagerholm,

May Griffith,

Jean Meunier,

Isabelle Brunette

Publication year - 2016

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.15-18271

Subject(s) - keratoconus , stromal cell , corneal transplantation , medicine , implant , ophthalmology , cornea , corneal transplant , surgery , pathology

The current and projected shortage of transplantable human donor corneas has prompted the development of long-term alternatives to human donor tissue for corneal replacement. The biosynthetic stromal substitutes (BSS) characterized herein represent a potentially safe alternative to donor organ transplantation for anterior corneal stromal diseases. The goal of this phase 1 safety study was to characterize the three-dimensional (3D) corneal shape of the first 10 human patients implanted with a BSS and assess its stability over time.

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