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Unravelling Stimulus Direction Dependency of Visual Acuity in Larval Zebrafish by Consistent Eye Displacements Upon Optokinetic Stimulation
Author(s) -
Stefan Yu Bögli,
Maresa Afthinos,
Giovanni Bertolini,
Dominik Straumann,
Yingyu Huang
Publication year - 2016
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.15-18072
Subject(s) - optokinetic reflex , stimulus (psychology) , zebrafish , eye movement , visual acuity , biology , retinal , retina , anatomy , ophthalmology , audiology , neuroscience , medicine , psychology , biochemistry , gene , psychotherapist
Impairment of visual acuity (VA) can be seen early on in various diseases and has a major impact on patients' daily activities. Zebrafish is an important model for studying visual disorders. We developed a new method in zebrafish larva to easily and precisely measure the VA, which should allow for better estimation of affected vision such as after genetic manipulation or pharmacologic intervention.

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