Open AccessCelecoxib and Pioglitazone as Potential Therapeutics for Regulating TGF-β–Induced Hyaluronan in Dysthyroid Myopathy
Author(s) -
Anny M. S. Cheng,
Han Yin,
Angus Chen,
YaWen Liu,
MeiChun Chuang,
Hua He,
Sean Tighe,
Hosam Sheha,
ShuLang Liao
Publication year - 2016
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.15-18018
Subject(s) - pioglitazone , celecoxib , myopathy , medicine , pharmacology , endocrinology , diabetes mellitus , type 2 diabetes
To investigate the role of extraocular muscles (EOM) myoblasts in Graves ophthalmopathy (GO) pathology and the effect of a cyclooxygenase (COX)-2 inhibitor and a peroxisome proliferator-activated receptor (PPAR)-γ agonist in its treatment.
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