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Altered Transport Velocity of Axonal Mitochondria in Retinal Ganglion Cells After Laser-Induced Axonal Injury In Vitro
Author(s) -
Satoshi Yokota,
Yuji Takihara,
Shogo Arimura,
Seiji Miyake,
Yoshihiro Takamura,
Nagahisa Yoshimura,
Masaru Inatani
Publication year - 2015
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.15-17876
Subject(s) - axoplasmic transport , retinal ganglion cell , mitochondrion , optic nerve , diffuse axonal injury , biology , apoptosis , microbiology and biotechnology , anatomy , medicine , traumatic brain injury , biochemistry , psychiatry
Axonal damage precedes retinal ganglion cell (RGC) apoptosis in glaucomatous optic neuropathy. Because mitochondria in RGC axons are damaged before cell death, we examined axonal mitochondrial transport dynamics after axonal injury.

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