MicroRNA Profiling in Aqueous Humor of Individual Human Eyes by Next-Generation Sequencing | Zendy

Thomas Wecker | Zendy; Klaus Hoffmeier | Zendy; Anne Plötner | Zendy; Björn Grüning | Zendy; Ralf Horres | Zendy; Rolf Backofen | Zendy; Thomas Reinhard | Zendy; Günther Schlunck | Zendy

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MicroRNA Profiling in Aqueous Humor of Individual Human Eyes by Next-Generation Sequencing

Author(s) -

Thomas Wecker,

Klaus Hoffmeier,

Anne Plötner,

Björn Grüning,

Ralf Horres,

Rolf Backofen,

Thomas Reinhard,

Günther Schlunck

Publication year - 2016

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.15-17828

Subject(s) - microrna , aqueous humor , biology , computational biology , microvesicles , wnt signaling pathway , microbiology and biotechnology , genetics , gene , medicine , ophthalmology

Extracellular microRNAs (miRNAs) in aqueous humor were suggested to have a role in transcellular signaling and may serve as disease biomarkers. The authors adopted next-generation sequencing (NGS) techniques to further characterize the miRNA profile in single samples of 60 to 80 μL human aqueous humor.

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