Open AccessMicroRNA-184 Regulates Corneal Lymphangiogenesis
Author(s) -
Sammy Grimaldo,
Don Yuen,
Jaci Theis,
Melissa Ng,
Tatiana Ecoiffier,
Lu Chen
Publication year - 2015
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.15-17733
Subject(s) - lymphangiogenesis , microrna , ophthalmology , medicine , biology , genetics , cancer , metastasis , gene
MicroRNAs are a class of small noncoding RNAs that negatively regulate gene expression by binding to complimentary sequences of target messenger RNA. Their roles in corneal lymphangiogenesis are largely unknown. This study was to investigate the specific role of microRNA-184 (mir-184) in corneal lymphangiogenesis (LG) in vivo and lymphatic endothelial cells (LECs) in vitro.
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