Enhanced Motion Aftereffects in Migraine Are Related to Contrast Sensitivity: Implications for Models of Differences in Precortical/Cortical Function

Visual tests can be used as noninvasive tools to test models of the pathophysiology underlying neurological conditions, such as migraine. For example, there are reports that the motion aftereffect, which involves neural processing in several cortical areas, is prolonged in migraine. There also are reports of impaired contrast sensitivity in migraine, however, attributed to a precortical dysfunction. This study explored associations between these two tests of visual function. Specifically, it aimed to clarify whether the magnitude of the motion aftereffect is affected by contrast and contrast sensitivity.