Comparative Proteomic Analysis of Two Uveitis Models in Lewis Rats | Zendy

Kathryn L. Pepple | Zendy; Lauren Rotkis | Zendy; Leslie Wilson | Zendy; Angela Sandt | Zendy; Russell N. Van Gelder | Zendy

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Comparative Proteomic Analysis of Two Uveitis Models in Lewis Rats

Author(s) -

Kathryn L. Pepple,

Lauren Rotkis,

Leslie Wilson,

Angela Sandt,

Russell N. Van Gelder

Publication year - 2015

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.15-17524

Subject(s) - uveitis , s100a9 , s100a8 , chemistry , proinflammatory cytokine , western blot , inflammation , aqueous solution , calprotectin , microbiology and biotechnology , biochemistry , medicine , immunology , biology , pathology , disease , inflammatory bowel disease , gene

Inflammation generates changes in the protein constituents of the aqueous humor. Proteins that change in multiple models of uveitis may be good biomarkers of disease or targets for therapeutic intervention. The present study was conducted to identify differentially-expressed proteins in the inflamed aqueous humor.

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