Integrin Alpha-9 Mediates Lymphatic Valve Formation in Corneal Lymphangiogenesis | Zendy

Eda I. Altiok | Zendy; Tatiana Ecoiffier | Zendy; Roberto Sessa | Zendy; Don Yuen | Zendy; Sammy Grimaldo | Zendy; Colin Tran | Zendy; David Li | Zendy; Michael Rosner | Zendy; Narae Lee | Zendy; Toshimitsu Uede | Zendy; Lu Chen | Zendy

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Integrin Alpha-9 Mediates Lymphatic Valve Formation in Corneal Lymphangiogenesis

Author(s) -

Eda I. Altiok,

Tatiana Ecoiffier,

Roberto Sessa,

Don Yuen,

Sammy Grimaldo,

Colin Tran,

David Li,

Michael Rosner,

Narae Lee,

Toshimitsu Uede,

Lu Chen

Publication year - 2015

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.15-17509

Subject(s) - lymphangiogenesis , lymphatic system , integrin , lymphatic vessel , microbiology and biotechnology , alpha (finance) , lymphatic endothelium , chemistry , medicine , biology , immunology , receptor , cancer , surgery , metastasis , construct validity , patient satisfaction

We recently reported that corneal lymphatic vessels develop integrin alpha-9 (Itga-9)-positive valves during inflammatory lymphangiogenesis. The purpose of this study was to further investigate the role of Itga-9 in corneal lymphatic valve formation in vivo and lymphatic endothelial cell (LEC) functions in vitro.

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