Vascular Normalization by ROCK Inhibitor: Therapeutic Potential of Ripasudil (K-115) Eye Drop in Retinal Angiogenesis and Hypoxia | Zendy

Muneo Yamaguchi | Zendy; Shintaro Nakao | Zendy; Ryoichi Arita | Zendy; Yoshihiro Kaizu | Zendy; Mitsuru Arima | Zendy; Yedi Zhou | Zendy; Takeshi Kita | Zendy; Shigeo Yoshida | Zendy; Kazuhiro Kimura | Zendy; Tomoyuki Isobe | Zendy; Yoshio Kaneko | Zendy; KohHei Sonoda | Zendy; Tatsuro Ishibashi | Zendy

Open Access

Vascular Normalization by ROCK Inhibitor: Therapeutic Potential of Ripasudil (K-115) Eye Drop in Retinal Angiogenesis and Hypoxia

Author(s) -

Muneo Yamaguchi,

Shintaro Nakao,

Ryoichi Arita,

Yoshihiro Kaizu,

Mitsuru Arima,

Yedi Zhou,

Takeshi Kita,

Shigeo Yoshida,

Kazuhiro Kimura,

Tomoyuki Isobe,

Yoshio Kaneko,

KohHei Sonoda,

Tatsuro Ishibashi

Publication year - 2016

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.15-17411

Subject(s) - fasudil , retinal , retina , chemistry , rho associated protein kinase , pharmacology , hypoxia (environmental) , phosphorylation , biology , biochemistry , oxygen , organic chemistry , neuroscience

In this study, we investigated the therapeutic potential of a Rho-associated coiled-coil-containing protein kinase (ROCK) inhibitor ripasudil (K-115) eye drop on retinal neovascularization and hypoxia.

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