Adenosine A1Receptors Selectively Modulate Oxygen-Induced Retinopathy at the Hyperoxic and Hypoxic Phases by Distinct Cellular Mechanisms | Zendy

Shuya Zhang | Zendy; Haiyan Li | Zendy; Bo Li | Zendy; Dingjuan Zhong | Zendy; Xuejiao Gu | Zendy; Lingyun Tang | Zendy; Yanyan Wang | Zendy; Cun Wang | Zendy; Rong Zhou | Zendy; Yan Li | Zendy; Yan He | Zendy; Mozi Chen | Zendy; Yuqing Huo | Zendy; Xiao-Ling Liu | Zendy; JiangFan Chen | Zendy

Open Access

Adenosine A₁Receptors Selectively Modulate Oxygen-Induced Retinopathy at the Hyperoxic and Hypoxic Phases by Distinct Cellular Mechanisms

Author(s) -

Shuya Zhang,

Haiyan Li,

Bo Li,

Dingjuan Zhong,

Xuejiao Gu,

Lingyun Tang,

Yanyan Wang,

Cun Wang,

Rong Zhou,

Yan Li,

Yan He,

Mozi Chen,

Yuqing Huo,

Xiao-Ling Liu,

JiangFan Chen

Publication year - 2015

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.15-17202

Subject(s) - retinopathy of prematurity , retinal , retina , hyperoxia , biology , tunel assay , gliosis , apoptosis , microbiology and biotechnology , pathology , medicine , biochemistry , neuroscience , lung , genetics , pregnancy , gestational age

We critically evaluated the role of the adenosine A1 receptor (A1R) in normal development of retinal vasculature and pathogenesis of retinopathy of prematurity (ROP) by using the A1R knockout (KO) mice and oxygen-induced retinopathy (OIR) model.

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