Open AccessSingle Nucleotide Polymorphisms in the BDNF, VDR, and DNASE 1 Genes in Dry Eye Disease Patients: A Case-Control Study
Author(s) -
Joelle Hallak,
Sapna Tibrewal,
Neil Mohindra,
Xiaoyi Gao,
Sandeep Jain
Publication year - 2015
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.15-17036
Subject(s) - single nucleotide polymorphism , rs6265 , minor allele frequency , calcitriol receptor , snp , genotype , genotyping , allele , odds ratio , genetics , medicine , allele frequency , snp genotyping , biology , gene
To identify single nucleotide polymorphisms (SNPs) in the brain-derived neurotrophic factor (BDNF), vitamin D receptor (VDR), and DNASE1 genes that may be associated with dry eye disease (DED), and determine whether this association varies by the presence of depression.