Open AccessCorneal Sensitivity Following Lacrimal Gland Excision in the Rat
Author(s) -
Ian D. Meng,
Stephen Barton,
Neal E. Mecum,
Masayuki Kurose
Publication year - 2015
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.15-16717
Subject(s) - medicine , lacrimal gland , hypertonic saline , anesthesia , nociception , cornea , saline , ophthalmology , pathology , receptor
Dry eye disease (DED) produces ocular pain and irritation, yet a detailed characterization of ocular sensitivity in a preclinical model of DED is lacking. The aim of the present study was to assess nociceptive behaviors in an aqueous tear deficiency model of DED in the rat.
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