Roles of Epithelial Cell–Derived Type 2–Initiating Cytokines in Experimental Allergic Conjunctivitis | Zendy

Yosuke Asada | Zendy; Susumu Nakae | Zendy; Waka Ishida | Zendy; Kanji Hori | Zendy; Jobu Sugita | Zendy; Katsuko Sudo | Zendy; Ken Fukuda | Zendy; Atsuki Fukushima | Zendy; Hajime Suto | Zendy; Akira Murakami | Zendy; Hirohisa Saito | Zendy; Nobuyuki Ebihara | Zendy; Akira Matsuda | Zendy

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Roles of Epithelial Cell–Derived Type 2–Initiating Cytokines in Experimental Allergic Conjunctivitis

Author(s) -

Yosuke Asada,

Susumu Nakae,

Waka Ishida,

Kanji Hori,

Jobu Sugita,

Katsuko Sudo,

Ken Fukuda,

Atsuki Fukushima,

Hajime Suto,

Akira Murakami,

Hirohisa Saito,

Nobuyuki Ebihara,

Akira Matsuda

Publication year - 2015

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.15-16563

Subject(s) - thymic stromal lymphopoietin , immunoglobulin e , immunology , interleukin 4 , eotaxin , eosinophil , medicine , cytokine , interleukin , interleukin 5 , antibody , asthma

To clarify the possible involvement of the type 2-initiating cytokines interleukin (IL)-25, IL-33, and thymic stromal lymphopoietin (TSLP) in the pathophysiology of allergic conjunctivitis, we evaluated ragweed (RW)-induced experimental allergic conjunctivitis (EAC) models by using IL-25 knockout (KO), IL-33 KO, and TSLP receptor (TSLPR) KO mice.

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