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MMP14 Cleavage of VEGFR1 in the Cornea Leads to a VEGF-Trap Antiangiogenic Effect
Author(s) -
Kyu-Yeon Han,
Jennifer DugasFord,
Hyun Lee,
Jin-Hong Chang,
Dimitri T. Azar
Publication year - 2015
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.14-16248
Subject(s) - cleavage (geology) , microbiology and biotechnology , chemistry , angiogenesis , matrix metalloproteinase , edman degradation , metalloproteinase , recombinant dna , proteolysis , coomassie brilliant blue , vascular endothelial growth factor , biochemistry , biology , peptide sequence , vegf receptors , enzyme , staining , cancer research , paleontology , fracture (geology) , gene , genetics
To determine the possible antiangiogenic effect of metalloproteinase (MMP) 14 cleavage of vascular endothelial growth factor receptor 1 (VEGFR1) in the cornea.

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