Open AccessPseudo-Fovea Formation After Gene Therapy for RPE65-LCA
Author(s) -
Artur V. Cideciyan,
Geoffrey K. Aguirre,
Samuel G. Jacobson,
Omar H. Butt,
Sharon Schwartz,
Małgorzata Świder,
Alejandro J. Román,
Sam Sadigh,
William W. Hauswirth
Publication year - 2014
Publication title -
investigative ophthalmology and visual science
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.14-15895
Subject(s) - cis trans isomerases , retinal , retina , ophthalmology , fixation (population genetics) , rpe65 , medicine , fovea centralis , biology , neuroscience , retinal pigment epithelium , foveal , gene , peptidylprolyl isomerase , population , biochemistry , environmental health , isomerase
The purpose of this study was to evaluate fixation location and oculomotor characteristics of 15 patients with Leber congenital amaurosis (LCA) caused by RPE65 mutations (RPE65-LCA) who underwent retinal gene therapy.